(R)-Nepicastat HCl ( —— )

产品货号. M17411 CAS No. 195881-94-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

(R)-Nepicastat HCl
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

(R)-Nepicastat HCl 是 Nepicastat HCl 的 R 对映异构体，是一种有效的选择性抑制剂，对牛和人多巴胺-β-羟化酶的 IC50 分别为 25.1 nM 和 18.3 nM，对 12 种其他酶和 13 种神经递质受体的亲和力可忽略不计。
产品描述

(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
体外实验

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体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

Dopamine β-hydroxylase| Dopamine β-hydroxylase
研究领域

Cardiovascular Disease
适应症

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1. Stanley WC, et al. Br J Pharmacol. 1997, 121(8), 1803-1809.

计算器

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